Body temperature cycles: Gatekeepers of circadian clocks
نویسندگان
چکیده
منابع مشابه
Rhythms of Mammalian Body Temperature Can Sustain Peripheral Circadian Clocks
BACKGROUND Low-amplitude temperature oscillations can entrain the phase of circadian rhythms in several unicellular and multicellular organisms, including Neurospora and Drosophila. Because mammalian body temperature is subject to circadian variations of 1 degrees C-4 degrees C, we wished to determine whether these temperature cycles could serve as a Zeitgeber for circadian gene expression in p...
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متن کاملBody temperature cycles
Body temperature in mammals is homeostatically regulated around a set point, which renders it independent of large variations in environmental temperature. Hypothalamic regions, including the preoptic area, act as thermoregulatory centers that receive temperature inputs from the core body through hypothalamic receptors and from the environment through skin receptors. Thermogenic and heatdissipa...
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A small cluster of approximately 20,000 neurons in the ventral hypothalamus provide the body with key time-keeping signals and drive circadian rhythms. This circadian clock exhibits surprisingly complex substructures, with inputs from the retina, and outputs to other brain structures. Rather little is known of the neurotransmitters involved, or their regulation.
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ژورنال
عنوان ژورنال: Cell Cycle
سال: 2013
ISSN: 1538-4101,1551-4005
DOI: 10.4161/cc.23670